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Superoxide Dismutase 1 Rabbit mAb

263564

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N263564
Product Name:   Anti-Superoxide Dismutase 1 Rabbit Monoclonal Antibody
Synonyms:   SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1
UNIPROT ID:   P00441
Background:    SOD1, Cu/Zn superoxide dismutase, is a major antioxidant enzyme that catalyzes the conversion of superoxide anion to hydrogen peroxide and molecular oxygen. The mechanism by which mutant SOD1 induces the neurodegeneration observed in ALS is still unclear. Mutant SOD1 proteins become misfolded and consequently oligomerize into high molecular weight species that aggregate and end up in proteinaceous inclusions.
Immunogen:    A synthetic peptide of human Superoxide Dismutase 1
Applications:    WB,IHC-F,IHC-P,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R08-5A5
MW:    Calculated MW: 16 kDa; Observed MW: 16 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human breast cancer tissue using Superoxide Dismutase 1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunocytochemistry analysis of Superoxide Dismutase 1 (green) in HCT116 using Superoxide Dismutase 1 antibody,and DAPI(blue).

Western blot analysis of Superoxide Dismutase 1 in A549, HL-60, C6 lysates using Superoxide Dismutase 1 antibody.
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