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Cyclin H Rabbit mAb

263290

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N263290
Product Name:   Anti-Cyclin H Rabbit Monoclonal Antibody
Synonyms:   CCNH; Cyclin-H; MO15-associated protein; p34; p37
UNIPROT ID:   P51946
Background:    Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
Immunogen:    A synthetic peptide of human Cyclin H/p34
Applications:    WB,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R02-4I4
MW:    Calculated MW: 38 kDa; Observed MW: 38 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Cyclin H/p34 in U251, HL-60, Lncap lysates using Cyclin H/p34 antibody

Immunocytochemistry analysis of Cyclin H (green) in Hela using Cyclin H antibody,and DAPI(blue).

Western blot analysis of Cyclin H/p34 in 3T3 lysates using Cyclin H/p34 antibody.
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