Size：100 μl
Price：$ 349
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: N263242 | ||
| Product Name: Anti-BUBR1 Rabbit Monoclonal Antibody | ||
| Synonyms: BUB1B; BUBR1; MAD3L; SSK1; Mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MAD3/BUB1-related protein kinase; hBUBR1; Mitotic checkpoint kinase MAD3L; Protein SSK1 | ||
| UNIPROT ID: O60566 | ||
| Background: Essential component of the mitotic checkpoint. Required for normal mitosis progression. The mitotic checkpoint delays anaphase until all chromosomes are properly attached to the mitotic spindle. One of its checkpoint functions is to inhibit the activity of the anaphase-promoting complex/cyclosome (APC/C) by blocking the binding of CDC20 to APC/C, independently of its kinase activity. The other is to monitor kinetochore activities that depend on the kinetochore motor CENPE. Required for kinetochore localization of CENPE. | ||
| Immunogen: A synthetic peptide of human BubR1 | ||
| Applications: WB,ICC/IF,IP | ||
| Recommended Dilutions: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20 | ||
| Host Species: Rabbit | ||
| Clonality: Rabbit Monoclonal | ||
| Clone ID: R01-4C1 | ||
| MW: Calculated MW: 120 kDa; Observed MW: 120 kDa | ||
| Isotype: IgG | ||
| Purification: Affinity Purified | ||
| Species Reactivity: Human | ||
| Conjugation: Unconjugated | ||
| Modification: Unmodified | ||
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||
| Research Areas: Cell Biology | ||
| Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase
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