Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: N263199 | ||||
Product Name: Anti-Phospho-TAOK1/2/3 (Ser181/Ser181/Ser177) Rabbit Monoclonal Antibody | ||||
Synonyms: DPK; JIK; hKFC-A; MAP3K18 | ||||
UNIPROT ID: Q7L7X3/Q9H2K8/Q9UL54 | ||||
Background: Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. Phosphorylates MAP2K3, MAP2K6 and MARK2. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of the upstream MAP2K3 and MAP2K6 kinases. Involved in G-protein coupled receptor signaling to p38/MAPK14. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of MAP2K3 and MAP2K6. | ||||
Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser181 of human TAOK1 | ||||
Applications: WB,IHC-P | ||||
Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 | ||||
Host Species: Rabbit | ||||
Clonality: Rabbit Monoclonal | ||||
Clone ID: R04-3I5 | ||||
MW: Calculated MW: 116 kDa; Observed MW: 105,116,138 kDa | ||||
Isotype: IgG | ||||
Purification: Affinity Purified | ||||
Species Reactivity: Human,Mouse,Rat | ||||
Conjugation: Unconjugated | ||||
Modification: Phosphorylated | ||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||||
Research Areas: - | ||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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