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Phospho-TAOK1/2/3 (Ser181/Ser181/Ser177) Rabbit mAb

263199

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N263199
Product Name:   Anti-Phospho-TAOK1/2/3 (Ser181/Ser181/Ser177) Rabbit Monoclonal Antibody
Synonyms:   DPK; JIK; hKFC-A; MAP3K18
UNIPROT ID:   Q7L7X3/Q9H2K8/Q9UL54
Background:    Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. Phosphorylates MAP2K3, MAP2K6 and MARK2. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of the upstream MAP2K3 and MAP2K6 kinases. Involved in G-protein coupled receptor signaling to p38/MAPK14. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of MAP2K3 and MAP2K6.
Immunogen:    A synthetic phosphopeptide corresponding to residues surrounding Ser181 of human TAOK1
Applications:    WB,IHC-P
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R04-3I5
MW:    Calculated MW: 116 kDa; Observed MW: 105,116,138 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Phosphorylated
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    -
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human tonsil using TAOK1 (Phospho-Ser181)/TAOK2 (Phospho-Ser181)/TAOK3 (Phospho-Ser177) antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of Phospho-TAOK1(Ser181)/TAOK2 (Ser181)/TAOK3 (Ser177) in 3T3 lysates using Phospho-TAOK1/2/3 (Ser181/Ser181/Ser177) antibody.

Western blot analysis of TAOK1 (Phospho-Ser181)/TAOK2 (Phospho-Ser181)/TAOK3 (Phospho-Ser177) in Hela, A549, HL-60, U2OS, C6 lysates using TAOK1 (Phospho-Ser181)/TAOK2 (Phospho-Ser181)/TAOK3 (Phospho-Ser177) antibody.
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