Size：100 μl
Price：$ 349
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: N263175 | ||||
| Product Name: Anti-Phospho-MCM2 (Ser27) Rabbit Monoclonal Antibody | ||||
| Synonyms: MCM2; BM28; CCNL1; CDCL1; KIAA0030; DNA replication licensing factor MCM2; Minichromosome maintenance protein 2 homolog; Nuclear protein BM28 | ||||
| UNIPROT ID: P49736 | ||||
| Background: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012] | ||||
| Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser27 of human MCM2 | ||||
| Applications: WB,IHC-F,IHC-P,ICC/IF,IP | ||||
| Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 | ||||
| Host Species: Rabbit | ||||
| Clonality: Rabbit Monoclonal | ||||
| Clone ID: R08-4D8 | ||||
| MW: Calculated MW: 102 kDa; Observed MW: 125 kDa | ||||
| Isotype: IgG | ||||
| Purification: Affinity Purified | ||||
| Species Reactivity: Human | ||||
| Conjugation: Unconjugated | ||||
| Modification: Phosphorylated | ||||
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||||
| Research Areas: Epigenetics and Nuclear Signaling | ||||
| Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase
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