Size：100 μl
Price：$ 349
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: N263513 |
| Product Name: Anti-PTP4A2 Rabbit Monoclonal Antibody |
| Synonyms: protein tyrosine phosphatase type IVA; member 2; HH13; OV-1; PRL2; HH7-2; PRL-2; PTP4A; HU-PP-1; PTPCAAX2; ptp-IV1a; ptp-IV1b |
| UNIPROT ID: Q12974 |
| Background: The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. |
| Immunogen: A synthetic peptide of human PTP4A2/PRL2 |
| Applications: WB,IP |
| Recommended Dilutions: WB: 1/500-1/1000 IP: 1/20 |
| Host Species: Rabbit |
| Clonality: Rabbit Monoclonal |
| Clone ID: R02-1H6 |
| MW: Calculated MW: 19 kDa; Observed MW: 19 kDa |
| Isotype: IgG |
| Purification: Affinity Purified |
| Species Reactivity: Human |
| Conjugation: Unconjugated |
| Modification: Unmodified |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
| Research Areas: Cell Biology |
| Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
Western blot analysis of PTP4A2/PRL2 in Hela, A549, HL-60 lysates using PTP4A2 antibody. |
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase
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