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Caspase 7 Rabbit mAb

263507

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N263507
Product Name:   Anti-Caspase 7 Rabbit Monoclonal Antibody
Synonyms:   MCH3; CMH-1; LICE2; CASP-7; ICE-LAP3
UNIPROT ID:   P55210
Background:    Belongs to the peptidase C14A family. Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp--Gly-217' bond. Overexpression promotes programmed cell death.
Immunogen:    A synthetic peptide of human pro Caspase-7
Applications:    WB,IHC-P
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R03-0F2
MW:    Calculated MW: 34 kDa; Observed MW: 34 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    apoptosis - Caspase family
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human Cholangiocarcinoma using pro Caspase7 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of Caspase7 in A549, MCF-7, 293T lysates using Caspase 7 antibody.
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