Size：100 μl
Price：$ 349
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: N263506 |
| Product Name: Anti-PRAS40 Rabbit Monoclonal Antibody |
| Synonyms: AKT1S1; PRAS40; Proline-rich AKT1 substrate 1; 40 kDa proline-rich AKT substrate |
| UNIPROT ID: Q96B36 |
| Background: PRAS40 interacts with Raptor in mTOR complex 1 (mTORC1) in insulin-deprived cells and inhibits the activation of the mTORC1 pathway mediated by the cell cycle protein Rheb. Phosphorylation of PRAS40 by Akt at Thr246 relieves PRAS40 inhibition of mTORC1. mTORC1 in turn phosphorylates PRAS40 at Ser183. |
| Immunogen: A synthetic peptide of human PRAS40 |
| Applications: WB,IP |
| Recommended Dilutions: WB: 1/500-1/1000 IP: 1/20 |
| Host Species: Rabbit |
| Clonality: Rabbit Monoclonal |
| Clone ID: R05-3A5 |
| MW: Calculated MW: 27 kDa; Observed MW: 40 kDa |
| Isotype: IgG |
| Purification: Affinity Purified |
| Species Reactivity: Human,Rat |
| Conjugation: Unconjugated |
| Modification: Unmodified |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
| Research Areas: Cell Biology |
| Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
Western blot analysis of PRAS40 in Hela, A549, C6 lysates using PRAS40 antibody. |
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase
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