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Paxillin Rabbit mAb

263481

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N263481
Product Name:   Anti-Paxillin Rabbit Monoclonal Antibody
Synonyms:   PXN; Paxillin
UNIPROT ID:   P49023
Background:    Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). PXN is a multi-domain cytoskeletal protein that localizes primarily to focal adhesion sites to the extracellular matrix. Phosphorylated by focal adhesion kinase (FAK) and is a component of integrin signaling. Its phosphorylation provides docking sites for recruitment of signaling molecules to focal adhesions.
Immunogen:    A synthetic peptide of human Paxillin
Applications:    WB,IHC-P,IP
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R07-1B4
MW:    Calculated MW: 65 kDa; Observed MW: 65 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Rat,Hamster
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Paxillin antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of Paxillin in Hela lysates using Paxillin antibody.

Western blot analysis of Paxillin in CHO-K1, C6 lysates using Paxillin antibody.
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