Size：100 μl
Price：$ 349
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: N263400 | ||||
| Product Name: Anti-Lamin A/C Rabbit Monoclonal Antibody | ||||
| Synonyms: LMNA; LMN1; Prelamin-A/C | ||||
| UNIPROT ID: P02545 | ||||
| Background: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Play an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics.Prelamin-A/C can accelerate smooth muscle cell senescence. It acts to disrupt mitosis and induce DNA damage in vascular smooth muscle cells (VSMCs), leading to mitotic failure, genomic instability, and premature senescence. | ||||
| Immunogen: A synthetic peptide of human Lamin A/C | ||||
| Applications: WB,IHC-F,IHC-P,ICC/IF | ||||
| Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 | ||||
| Host Species: Rabbit | ||||
| Clonality: Rabbit Monoclonal | ||||
| Clone ID: R07-1I5 | ||||
| MW: Calculated MW: 74 kDa; Observed MW: 74,63 kDa | ||||
| Isotype: IgG | ||||
| Purification: Affinity Purified | ||||
| Species Reactivity: Human,Mouse | ||||
| Conjugation: Unconjugated | ||||
| Modification: Unmodified | ||||
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||||
| Research Areas: Tags & Cell Markers | ||||
| Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase
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