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Insulin Degrading Enzyme Rabbit mAb

263387

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N263387
Product Name:   Anti-Insulin Degrading Enzyme Rabbit Monoclonal Antibody
Synonyms:   INSULYSIN; Insulin degrading enzyme; IDE
UNIPROT ID:   P14735
Background:    This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid.
Immunogen:    A synthetic peptide of human Insulin degrading enzyme/IDE
Applications:    WB,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R04-4E8
MW:    Calculated MW: 118 kDa; Observed MW: 118 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of Insulin degrading enzyme/IDE (green) in hela using Insulin degrading enzyme/IDE antibody,and DAPI(blue)

Western blot analysis of Insulin degrading enzyme/IDE in A549, HL-60, U2OS lysates using Insulin Degrading Enzyme antibody.
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