Size：100 μl
Price：$ 349
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: N263361 | ||||
| Product Name: Anti-HIF1 beta Rabbit Monoclonal Antibody | ||||
| Synonyms: ARNT; BHLHE2; Aryl hydrocarbon receptor nuclear translocator; ARNT protein; Class E basic helix-loop-helix protein 2; bHLHe2; Dioxin receptor; nuclear translocator; Hypoxia-inducible factor 1-beta; HIF-1-beta; HIF1-beta | ||||
| UNIPROT ID: P27540 | ||||
| Background: HIF-1β is also known as AhR nuclear translocator (ARNT) due to its ability to partner with the aryl hydrocarbon receptor (AhR) to form a heterodimeric transcription factor complex. Together with AhR, HIF-1β plays an important role in xenobiotics metabolism. In addition, a chromosomal translocation leading to a TEL-ARNT fusion protein is associated with acute myeloblastic leukemia. Studies also found that ARNT/HIF-1β expression levels decrease significantly in pancreatic islets from patients with type 2 diabetes, suggesting that HIF-1β plays an important role in pancreatic β-cell function. | ||||
| Immunogen: Recombinant protein of human HIF1 beta | ||||
| Applications: WB,IHC-P | ||||
| Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 | ||||
| Host Species: Rabbit | ||||
| Clonality: Rabbit Monoclonal | ||||
| Clone ID: R05-3B2 | ||||
| MW: Calculated MW: 87 kDa; Observed MW: 87 kDa | ||||
| Isotype: IgG | ||||
| Purification: Affinity Purified | ||||
| Species Reactivity: Human,Mouse,Rat,Hamster | ||||
| Conjugation: Unconjugated | ||||
| Modification: Unmodified | ||||
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||||
| Research Areas: Hypoxia Signal Transductionyyyyy Hypoxia-induced | ||||
| Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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