Size：100 μl
Price：$ 349
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: N263317 | ||||
| Product Name: Anti-Ephrin Receptor B4 Rabbit Monoclonal Antibody | ||||
| Synonyms: EPHB4; HTK; MYK1; TYRO11; Ephrin type-B receptor 4; Hepatoma transmembrane kinase; Tyrosine-protein kinase TYRO11 | ||||
| UNIPROT ID: P54760 | ||||
| Background: EPH receptor B4 (EphB4), with 987-amino acid protein (about 108kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The Eph receptor tyrosine kinases and their ligands, the ephrins, regulate numerous biological processes in developing and adult tissues and have been implicated in cancer progression and in pathological forms of angiogenesis. EphB4 acts as a negative regulator of blood vessel branching and vascular network formation, switching the vascularization program from sprouting angiogenesis to circumferential vessel growth. EphB4 and its ligand ephrinB2 express in several kinds of tumor cells and correlate with tumorigenesis. EphB4 is thus a potential candidate as a predictor of disease outcome in several kinds of tumor and as target for novel therapy. | ||||
| Immunogen: Recombinant protein of human Eph receptor B4/HTK | ||||
| Applications: WB,IHC-P | ||||
| Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 | ||||
| Host Species: Rabbit | ||||
| Clonality: Rabbit Monoclonal | ||||
| Clone ID: R04-3B0 | ||||
| MW: Calculated MW: 108 kDa; Observed MW: 135 kDa | ||||
| Isotype: IgG | ||||
| Purification: Affinity Purified | ||||
| Species Reactivity: Human,Mouse,Rat | ||||
| Conjugation: Unconjugated | ||||
| Modification: Unmodified | ||||
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||||
| Research Areas: NeuroscienceyyyyyEphrin Receptor | ||||
| Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase
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