Size：100 μl
Price：$ 349
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: N263295 | ||
| Product Name: Anti-DAB2 Rabbit Monoclonal Antibody | ||
| Synonyms: DOC2; DOC-2 | ||
| UNIPROT ID: P98082 | ||
| Background: This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. | ||
| Immunogen: A synthetic peptide of human DAB2 | ||
| Applications: WB,IHC-P,IP | ||
| Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20 | ||
| Host Species: Rabbit | ||
| Clonality: Rabbit Monoclonal | ||
| Clone ID: R02-4H2 | ||
| MW: Calculated MW: 82 kDa; Observed MW: 96 kDa | ||
| Isotype: IgG | ||
| Purification: Affinity Purified | ||
| Species Reactivity: Human | ||
| Conjugation: Unconjugated | ||
| Modification: Unmodified | ||
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||
| Research Areas: Signal Transduction | ||
| Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase
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