Pioneering GTPase and Oncogene Product Development Since 2010
shoppingCardistributornews

Email Us:[email protected]

Call Us:(+1) 610-945-2007

Phospho-Rb (Thr356) Rabbit mAb

263194

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

Add to cart Buy now Download Datasheet MSDS
Product Description Reference citations(0) Related Products
Cat.#:   N263194
Product Name:   Anti-Phospho-Rb (Thr356) Rabbit Monoclonal Antibody
Synonyms:   RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110
UNIPROT ID:   P06400
Background:    Cell cycle-dependent phosphorylation by a CDK inhibits Rb target binding and allows cell cycle progression. Rb inactivation and subsequent cell cycle progression likely requires an initial phosphorylation by cyclin D-CDK4/6 followed by cyclin E-CDK2 phosphorylation. Specificity of different CDK/cyclin complexes has been observed in vitro and cyclin D1 is required for Ser780 phosphorylation in vivo.
Immunogen:    A synthetic phosphopeptide corresponding to residues surrounding Thr356 of human Rb
Applications:    WB,IHC-P,IP
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R04-1C4
MW:    Calculated MW: 106 kDa; Observed MW: 110 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Rat
Conjugation:    Unconjugated
Modification:    Phosphorylated
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human tonsil using Rb (Phospho-Thr356) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of Rb (Phospho-Thr356) in HL-60, U2OS, C6 lysates using Phospho-Rb (Thr356) antibody.
Reference citations
    No data available

Select By Alphabet

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z