Size：100 μl
Price：$ 349
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: N263191 | ||
| Product Name: Anti-Phospho-Rb (Ser608) Rabbit Monoclonal Antibody | ||
| Synonyms: RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110 | ||
| UNIPROT ID: P06400 | ||
| Background: Cell cycle-dependent phosphorylation by a CDK inhibits Rb target binding and allows cell cycle progression. Rb inactivation and subsequent cell cycle progression likely requires an initial phosphorylation by cyclin D-CDK4/6 followed by cyclin E-CDK2 phosphorylation. Specificity of different CDK/cyclin complexes has been observed in vitro and cyclin D1 is required for Ser780 phosphorylation in vivo. | ||
| Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser608 of human Rb | ||
| Applications: WB,IHC-P | ||
| Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 | ||
| Host Species: Rabbit | ||
| Clonality: Rabbit Monoclonal | ||
| Clone ID: R02-6C5 | ||
| MW: Calculated MW: 106 kDa; Observed MW: 110 kDa | ||
| Isotype: IgG | ||
| Purification: Affinity Purified | ||
| Species Reactivity: Human,Rat | ||
| Conjugation: Unconjugated | ||
| Modification: Phosphorylated | ||
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||
| Research Areas: Cell Biology | ||
| Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase
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