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Phospho-eIF4B (Ser406) Rabbit mAb

263161

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N263161
Product Name:   Anti-Phospho-eIF4B (Ser406) Rabbit Monoclonal Antibody
Synonyms:   EIF-4B; PRO1843
UNIPROT ID:   P23588
Background:    The eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA.It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. It promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both eIF4A and eIF4F
Immunogen:    A synthetic phosphopeptide corresponding to residues surrounding Ser406 of human eIF4B
Applications:    WB,IHC-P
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R05-4B2
MW:    Calculated MW: 69 kDa; Observed MW: 80 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Phosphorylated
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using eIF4B (Phospho-Ser406) antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of Phospho-eIF4B (Ser406) in mouse heart lysates using Phospho-eIF4B (Ser406) antibody.

Western blot analysis of eIF4B (Phospho-Ser406) in A549, HL-60, U2OS, C6 lysates using eIF4B (Phospho-Ser406) antibody.
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