PI3 Kinase p85 alpha (3H5) Mouse mAb

261374

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: N261374

Product Name: Anti-PI3 Kinase p85 alpha (3H5) Mouse Monoclonal Antibody

Synonyms: PIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha

UNIPROT ID: P27986

Background: Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

Immunogen: Purified recombinant protein expressed in E.coli.

Applications: WB,IHC-P

Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100

Host Species: Mouse

Clonality: Mouse Monoclonal

Clone ID: 3H5-1H4-9D2

MW: Calculated MW: 84 kDa; Observed MW: 84 kDa

Isotype: IgG1

Purification: Affinity Purified

Species Reactivity: Human,Mouse,Rat

Conjugation: Unconjugated

Modification: Unmodified

Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Research Areas: Signal Transduction

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemical analysis of paraffin-embedded Human tonsils using PI3 Kinase p85 alpha (3H5) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.	Immunohistochemistry analysis of paraffin-embedded rat Liver Tissue using PI3 Kinase p85 alpha (3H5) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Western blot analysis of PI3 Kinase p85 alpha (3H5) in THP-1, MCF-7, Goat Muscle, CHO-K1, C6, 3T3 lysates using PI3 Kinase p85 alpha (3H5) antibody	Western blot analysis of PI3 Kinase p85 alpha (3H5) in Hela, A549, HL-60, U2OS, C6 lysates using PI3 Kinase p85 alpha (3H5) antibody.

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PI3 Kinase p85 alpha (3H5) Mouse mAb

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