Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: S213283 | ||||
Product Name: Anti-CDH5 Rabbit Polyclonal Antibody | ||||
Synonyms: 7B4; CD144 | ||||
UNIPROT ID: P33151 (Gene Accession - NP_001786 ) | ||||
Background: This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined. | ||||
Immunogen: Synthetic peptide of human CDH5 | ||||
Applications: ELISA, IHC | ||||
Recommended Dilutions: IHC: 50-200; ELISA: 2000-20000 | ||||
Host Species: Rabbit | ||||
Clonality: Rabbit Polyclonal | ||||
Isotype: Immunogen-specific rabbit IgG | ||||
Purification: Antigen affinity purification | ||||
Species Reactivity: Human | ||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||
Research Areas: Signal Transduction, Cardiovascular | ||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase