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SETDB1 Rabbit pAb

212799

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Product Description Reference citations(0) Related Products
Cat.#:   S212799
Product Name:   Anti-SETDB1 Rabbit Polyclonal Antibody
Synonyms:   ESET; KG1T; KMT1E; TDRD21; H3-K9-HMTase4
UNIPROT ID:   Q15047 (Gene Accession - BC009362 )
Background:    This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.
Immunogen:    Fusion protein of human SETDB1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-300; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 212799(SETDB1 Antibody) at a dilution of 1/60(Nucleus and Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 212799(Anti-SETDB1 Antibody) at dilution 1/60.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 212799(Anti-SETDB1 Antibody) at a dilution of 1/60.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with fusion protein and then with D125846(Anti-SETDB1 Antibody) at dilution 1/60.
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