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PPP1R3C Rabbit pAb

212748

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   S212748
Product Name:   Anti-PPP1R3C Rabbit Polyclonal Antibody
Synonyms:   PTG; PPP1R5
UNIPROT ID:   Q9UQK1 (Gene Accession - BC012625 )
Background:    This gene encodes a carbohydrate binding protein that is a subunit of the protein phosphatase 1 (PP1) complex. PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities. The encoded protein affects glycogen biosynthesis by activating glycogen synthase and limiting glycogen breakdown by reducing glycogen phosphorylase activity. DNA hypermethylation of this gene has been found in colorectal cancer patients. The encoded protein also interacts with the laforin protein, which is a protein tyrosine phosphatase implicated in Lafora disease.
Immunogen:    Fusion protein of human PPP1R3C
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-300; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 212748(PPP1R3C Antibody) at a dilution of 1/50(Cytoplasm or Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the fusion protein and then with 212748(Anti-PPP1R3C Antibody) at dilution 1/50.

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 212748(Anti-PPP1R3C Antibody) at a dilution of 1/50.

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with fusion protein and then with D125728(Anti-PPP1R3C Antibody) at dilution 1/50.
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