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STX5 Rabbit pAb

212343

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   S212343
Product Name:   Anti-STX5 Rabbit Polyclonal Antibody
Synonyms:   SED5; STX5A
UNIPROT ID:   Q13190 (Gene Accession - BC012137 )
Background:   
Immunogen:    Fusion protein of human STX5
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: vesicle docking;WB: http://store.sangon.com/productImage/PIC/D124840/D124840-IHC-1-P.png;ELISA: In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with D124840(Anti-STX5 Antibody) at dilution 1/70.
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

and a 'short? 35 kDa isoform localized primarily to the Golgi. Formation of the syntaxin 5 SNARE comple

Bet1

allows for regulation of ER-to-Golgi transport

and endosome-to-Golgi retrograde transport. Research studies indicate that the syntaxin 5 SNARE complex also plays an essential role in autophagy following autophagosome formation. Intracellular protein transport mediated by the syntaxin 5 complex is required for transport and localized activity of lysosomal proteases. The experimental reduction or deletion of syntaxin 5 complex components results in non-functional lysosomes and accumulation of autophagosomes.""

http://store.sangon.com/productImage/APP/212343/212343-IHC-1-N.png
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