UBA7 Rabbit pAb

212066

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S212066

Product Name: Anti-UBA7 Rabbit Polyclonal Antibody

Synonyms: D8; UBE2; UBA1B; UBE1L

UNIPROT ID: P41226 (Gene Accession - BC006378 )

Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein.

Immunogen: Fusion protein of human UBA7

Applications: ELISA, IHC

Recommended Dilutions: IHC: 30-150; ELISA: 5000-10000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Epigenetics and Nuclear Signaling, Cancer, Cell Biology

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 212066(UBA7 Antibody) at a dilution of 1/35(Nucleus and Cytoplasm ).	In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the fusion protein and then with 212066(Anti-UBA7 Antibody) at dilution 1/35.
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 212066(Anti-UBA7 Antibody) at a dilution of 1/35.	In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with fusion protein and then with D124149(Anti-UBA7 Antibody) at dilution 1/35.

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UBA7 Rabbit pAb

TUBB3 Rabbit pAb

GAPDH Rabbit pAb

TUBA4A Rabbit pAb

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