HIF1A Rabbit pAb

211820

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

Add to cart

Download

Datasheet

MSDS

Product Description Reference citations(0) Related Products

Cat.#: S211820

Product Name: Anti-HIF1A Rabbit Polyclonal Antibody

Synonyms: HIF1; MOP1; PASD8; HIF-1A; bHLHe78; HIF-1alpha; HIF1-ALPHA

UNIPROT ID: Q16665 (Gene Accession - BC012527 )

Background: This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Immunogen: Fusion protein of human HIF1A

Applications: ELISA, IHC

Recommended Dilutions: IHC: 30-150; ELISA: 5000-10000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human, Mouse

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Cardiovascular, Epigenetics and Nuclear Signaling, Cancer, Metabolism

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 211820(HIF1A Antibody) at a dilution of 1/45(Cytoplasm or Nucleus).	In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the fusion protein and then with 211820(Anti-HIF1A Antibody) at dilution 1/45.
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 211820(Anti-HIF1A Antibody) at a dilution of 1/45.	In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with fusion protein and then with D123657(Anti-HIF1A Antibody) at dilution 1/45.

Reference citations

No data available

Product Targets

Product Categories

HIF1A Rabbit pAb

TUBB3 Rabbit pAb

GAPDH Rabbit pAb

TUBA4A Rabbit pAb

ALB Rabbit pAb

Contant Us