Size：100 μl
Price：$ 349
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: S211477 | ||
| Product Name: Anti-RASSF1 Rabbit Polyclonal Antibody | ||
| Synonyms: 123F2; RDA32; NORE2A; RASSF1A; REH3P21 | ||
| UNIPROT ID: Q9NS23 (Gene Accession - BC110412 ) | ||
| Background: This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. | ||
| Immunogen: Fusion protein of human RASSF1 | ||
| Applications: ELISA, IHC | ||
| Recommended Dilutions: IHC: 20-100; ELISA: 2000-5000 | ||
| Host Species: Rabbit | ||
| Clonality: Rabbit Polyclonal | ||
| Isotype: Immunogen-specific rabbit IgG | ||
| Purification: Antigen affinity purification | ||
| Species Reactivity: Human, Mouse | ||
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||
| Research Areas: Signal Transduction, Epigenetics and Nuclear Signaling, Cancer | ||
| Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase
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