Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: S210612 | ||||||
Product Name: Anti-SYT17 Rabbit Polyclonal Antibody | ||||||
Synonyms: sytXVII | ||||||
UNIPROT ID: Q9BSW7 (Gene Accession - BC004518 ) | ||||||
Background: Synaptotagmin XVII (SytXVII), also known as Synaptotagmin-17 (SYT17) or Protein B/K, is a 474 amino acid peripheral membrane protein that belongs to the Synaptotagmin family and contains two C2 domains. While expressed abundantly in brain (frontal and temporal lobes, hippocampus, hypothalamus, amygdala, substantia nigra and pituitary), kidney and prostate, Synaptotagmin XVII is also expressed in fetal brain, kidney and lung. The gene that encodes Synaptotagmin XVII contains 100,082 bases and maps to human chromosome 16p12.3. Encoding over 900 genes and consisting of approximately 90 million base pairs, chromosome 16 makes up nearly 3% of the human genome and is associated with a variety of genetic disorders, such as giant axonal neuropathy, Rubinstein-Taybi syndrome and Crohn's disease. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. | ||||||
Immunogen: Fusion protein of human SYT17 | ||||||
Applications: ELISA, WB, IHC | ||||||
Recommended Dilutions: IHC: 50-200;WB: 200-1000;ELISA: 1000-5000 | ||||||
Host Species: Rabbit | ||||||
Clonality: Rabbit Polyclonal | ||||||
Isotype: Immunogen-specific rabbit IgG | ||||||
Purification: Antigen affinity purification | ||||||
Species Reactivity: Human, Mouse, Rat | ||||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||||
Research Areas: Cell Biology | ||||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||||
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