Size：100 μl
Price：$ 349
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: S210508 | ||||||
| Product Name: Anti-TP63 Rabbit Polyclonal Antibody | ||||||
| Synonyms: AIS, KET, LMS, NBP, RHS, p40, p51, p63, EEC3, OFC8, p73H, p73L, SHFM4, TP53L, TP73L, p53CP, TP53CP, B(p51A), B(p51B) | ||||||
| UNIPROT ID: Q9H3D4 (Gene Accession - BC039815 ) | ||||||
| Background: This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. | ||||||
| Immunogen: Fusion protein of human TP63 | ||||||
| Applications: ELISA, WB, IHC | ||||||
| Recommended Dilutions: IHC: 25-100;WB: 200-1000;ELISA: 1000-2000 | ||||||
| Host Species: Rabbit | ||||||
| Clonality: Rabbit Polyclonal | ||||||
| Isotype: Immunogen-specific rabbit IgG | ||||||
| Purification: Antigen affinity purification | ||||||
| Species Reactivity: Human, Mouse, Rat | ||||||
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||||
| Research Areas: Epigenetics and Nuclear Signaling, Cancer | ||||||
| Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||||
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