Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: S210401 |
Product Name: Anti-IRF8 Rabbit Polyclonal Antibody |
Synonyms: ICSBP; IRF-8; ICSBP1; IMD32A; IMD32B; H-ICSBP |
UNIPROT ID: Q02556 (Gene Accession - BC126247 ) |
Background: Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. |
Immunogen: Fusion protein of human IRF8 |
Applications: ELISA, IHC |
Recommended Dilutions: IHC: 25-100; ELISA: 2000-5000 |
Host Species: Rabbit |
Clonality: Rabbit Polyclonal |
Isotype: Immunogen-specific rabbit IgG |
Purification: Antigen affinity purification |
Species Reactivity: Human, Mouse |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
Research Areas: Epigenetics and Nuclear Signaling, Immunology |
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin-embedded Human colorectal cancer tissue using 210401(IRF8 Antibody) at a dilution of 1/30(Nucleus). |
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