Size：100 μl
Price：$ 349
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: S210181 | ||||
| Product Name: Anti-CAPN6 Rabbit Polyclonal Antibody | ||||
| Synonyms: CANPX; CAPNX; CalpM; DJ914P14.1 | ||||
| UNIPROT ID: Q9Y6Q1 (Gene Accession - BC000730 ) | ||||
| Background: Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis. | ||||
| Immunogen: Fusion protein of human CAPN6 | ||||
| Applications: ELISA, WB, IHC | ||||
| Recommended Dilutions: IHC: 50-100;WB: 500-2000;ELISA: 5000-10000 | ||||
| Host Species: Rabbit | ||||
| Clonality: Rabbit Polyclonal | ||||
| Isotype: Immunogen-specific rabbit IgG | ||||
| Purification: Antigen affinity purification | ||||
| Species Reactivity: Human, Mouse, Rat | ||||
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||
| Research Areas: Signal Transduction, Cell Biology | ||||
| Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase
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