Size：100 μl
Price：$ 349
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: S210078 | ||||
| Product Name: Anti-NFKB1 Rabbit Polyclonal Antibody | ||||
| Synonyms: KBF1; EBP-1; NF-kB; CVID12; NF-kB1; NFKB-p50; NFkappaB; NF-kappaB; NFKB-p105; NF-kappa-B1; NF-kappabeta | ||||
| UNIPROT ID: P19838 (Gene Accession - BC051765 ) | ||||
| Background: This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. NFKB is a critical regulator of the immediate-early response to viral infection. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed. | ||||
| Immunogen: Fusion protein of human NFKB1 | ||||
| Applications: ELISA, WB, IHC | ||||
| Recommended Dilutions: IHC: 50-200;WB: 500-2000;ELISA: 5000-10000 | ||||
| Host Species: Rabbit | ||||
| Clonality: Rabbit Polyclonal | ||||
| Isotype: Immunogen-specific rabbit IgG | ||||
| Purification: Antigen affinity purification | ||||
| Species Reactivity: Human | ||||
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||
| Research Areas: Signal Transduction, Epigenetics and Nuclear Signaling, Cancer, Immunology | ||||
| Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase
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