Size:50 μg Price:$ 4400 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: 11011 | ||||
Product Name: Human CCR2 Full Length Protein | ||||
Size : 10 µg, 50 µg and 100 µg | ||||
Synonyms: CC-CKR-2; CCR-2; CCR2A; CCR2B; CD192; CKR2; CKR2A; CKR2B; CMKBR2; MCP-1-R | ||||
Target: CCR2 | ||||
UNIPROT ID: P41597 | ||||
Description: Human CCR2 full length protein-synthetic nanodisc | ||||
Background: The protein is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. | ||||
Species/Host: HEK293 | ||||
Molecular Weight: The human full length CCR2 protein has a MW of 41.9 kDa | ||||
Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. | ||||
Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. | ||||
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