Size:50 μg Price:$ 4400 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: 11016 | ||
Product Name: Human TRPA1 Full Length Protein | ||
Size : 10 µg, 50 µg and 100 µg | ||
Synonyms: ANKTM1; FEPS; FEPS1 | ||
Target: TRPA1 | ||
UNIPROT ID: O75762 | ||
Description: Human TRPA1 full length protein-synthetic nanodisc | ||
Background: The structure of the protein is highly related to both the protein ankyrin and transmembrane proteins. This protein is activated by a large variety of structurally unrelated electrophilic and non-electrophilic chemical compounds. Electrophilic ligands activate TRPA1 by interacting with critical N-terminal Cys residues in a covalent manner, whereas mechanisms of non-electrophilic ligands are not well determined. May be a component for the mechanosensitive transduction channel of hair cells in inner ear, thereby participating in the perception of sounds. Probably operated by a phosphatidylinositol second messenger system. | ||
Species/Host: HEK293 | ||
Molecular Weight: The human full length TRPA1 protein has a MW of 127.5 kDa | ||
Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. | ||
Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. | ||
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