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GAPDH pAb

21012S

Size:20 μl Price:$ 10 Brand:NewEast Place of Origin:USA Immunogen:

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GAPDH Polyclonal Antibody
Cat. #:  21012
Gene Symbol:  GAPDH
Description:   Anti-GAPDH Rabbit Polyclonal Antibody
Background:   Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate, an important energy-yielding step in carbohydrate metabolism. Additional functions of GAPDH include acting as a uricil DNA glycosylase, activating transcription, binding RNA and involvement in nuclear RNA export, DNA replication and DNA repair. Fuethermore, expression of GAPDH is upregulated in liver, lung and prostate cancers. Moreover, GAPDH complexes with neuronal proteins implicated in human neuro-degenerative disorders including the β-Amyloid precursor, Huntingtin and other triplet repeat neuronal disorder proteins.
Immunogen:   A synthetic peptide near the C-terminus of GAPDH of human origin
Applications:   ELISA, WB, IHC
Recommended Dilutions:    ELISA 1:100-1:5000 WB 1:100-1:2000 IHC 1:50-1:100
Concentration:   0.2 mg/ml
Host Species:   Rabbit
Format:   Liquid
Clonality:   Polyclonal
Isotype:   IgG
Purity:   Purified from serum
Preservative: No
Constituents:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  Anti-GAPDH antibody recognizes GAPDH of vertebrates
Storage Conditions:  Store at -20°C. Avoid repeated freezing and thawing
Western blot:   EC-1 cell lysate was used for Western blot with Anti-GAPDH polyclonal antibody (Cat # 21012).
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