Size：100 μl
Price：$ 495
Brand：NewEast 
Place of Origin：USA
Immunogen：
CTNNB1(T41I)
| Cat. #: 26306 |
| Gene Symbol: Beta-catenin, CTNNB, Catenin beta-1 |
| Description: Anti-CTNNB1(T41I) Mouse Monoclonal Antibody |
| Background: CTNNB1 protein is a dual function protein. It is a subunit of a complex of proteins that from adherent junctions, which are important for the establishment and maintenance of epithelial cell layers by regulating cell growth and adhesion between adjacent cells. CTNNB1 protein also pulls double duty as an intracellular signal transducer in the Wnt signaling pathway. Mutations of CTNNB1 have been implicated in the pathogenesis of several cancers. |
| Immunogen: A synthetic peptide from the internal region of CTNNB1 which includes the mutation of T41I, human origin. |
| Applications: ELISA, WB, IHC |
| Recommended Dilutions: ELISA: 1:1000-1:2000 WB: 1:500-1:1000 IHC: 1:50-1:100 |
| Concentration: 2 mg/ml |
| Host Species: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purified from ascites |
| Preservative: No |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Recognizes T41I mutant, but not wild type CTNNB1 of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
| Western blot: Western blot analysis of recombinant CTNNB1 (T41I) and wild type proteins. Purified His-tagged CTNNB1 (T41I) protein (lane2) and corresponding wild type protein (lane1) were blotted with Anti-CTNNB1(T41I) monoclonal antibody (Cat. #26306). Immunofluorescence: HEK293T cells were transfected with pCDNA3-GFP-CTNNB1 (WT) plasmid (left column) or pCDNA3-GFP-CTNNB1 (T41I) plasmid (right column), then fixed and stained with Anti-CTNNB1(T41I) monoclonal antibody (Cat. #26306). |
Select By Alphabet
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Subscribe to our latest email
(+1) 610-945-2007 [email protected] [email protected] 840 First Avenue, Suite 400, King of Prussia, PA 19406
Copyright © 2010 - 2024 NewEast Biosciences | All rights reserved
Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase
Add to cart
Buy now
Download
